Understanding the Molecular Mechanisms of Artificial Cannabinoid Receptor Agonists

G protein-coupled receptors (GPCRs) are important in health and disease. They allow cellular entry of hormones, neurotransmitters, therapeutics, and drugs such as cannabinoids. A novel cAMP bioluminescence biosensor system, known as CAYMEL BRET, helps researchers understand how synthetic cannabinoid receptor agonists (CRAs) activate GPCRs.¹

Learn more about how cAMP bioluminescence biosensing informs synthetic cannabinoid research.