T cells’ abilities to recognize molecular targets and orchestrate cytotoxic and immunomodulatory functions has made them attractive therapeutic tools, especially for cancer treatment. From CAR-T to tumor-infiltrating lymphocyte (TIL) therapeutics, the landscape continues to expand, as do new opportunities and challenges for researchers developing T cell immunotherapies.
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- An overview of the major current and emerging T cell immunotherapy classes
- Mechanisms of action, as well as strengths and limitations of each modality
- How limitations frame next-generation approaches to T cell immunotherapies
